DESCRIPTION

• Aa: 2-185
• Mw: 22 kDa
• Tags: N-terminal His-Tag
• Format: Aqueous buffer solution
• Genbank: NM_033360
• Species: Human
• Uniprot: P01116
• Shiptemp: -80°C (dry ice)
• Synonyms: C-K-RAS, CFC2, K-RAS2A
• Category: Cell Signaling/Protein
• References: 1. Roock, W., et al., JAMA. 2010: 304(16): 1812-1820.2. Kumar, S., et al., Gastrointestinal Cancer Research. 2014. Jan;7(1): 23-26.
• Description: Human KRAS also known as C-K-RAS, CFC2, and K-RAS2A, GenBank Accession No. NM_033360, a.a. 2-185, with G13D mutation and N-terminal His-tag, and expressed in a Baculovirus infected Sf9 cell expression system. MW=22 kDa.
• Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween20, 20% glycerol, 3 mM DTT, 180 mM Imidazole
• Supplied As: Aqueous buffer solution.
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. 
• Product Type: Protein
• Biosafety Level: Not applicable (BSL-1)
• Assay Conditions: Intrinsic GTPase reaction of KRAS (G13D) was conducted at room temperature for 60 min using GTPase-Glo (Promega) reagents with 1 µM GTP.
• Related Products: 100424, 100535, 100558, 100534
• Storage Stability: At least 6 months at -70°C.
• Scientific Category: Cell Signaling Pathway