STAT5A (pS780)

DETAILS

IHC: 2-10 µg/ml
PTM: Phosphorylated
Host: Rabbit
ELISA: 0.01-0.1 µg/ml
Gene ID: 6776
Isotype: Rabbit IgG
Clonality: Polyclonal Antibody
Immunogen: A synthetic peptide surrounding to the epitope -LDSRL-S-PPAGLF-with phosphorylation sites at Serine 780 of STAT5a protein from human, mouse, rat, chicken dog and bovine origins.
Background: STAT proteins (Signal transducer and activator of transcription) belong to a family of cytoplasmic transcription factors that can be phosphorylated by a lignad binding to its cell surface receptor. Activation of STAT5a induces dimerization, nuclear translocation and DNA binding. Stat5A is activated by IL-2, IL-7, IL-15, IL-3, GM-CSF, growth hormone, prolactin, erythropoietin and thrombopoietin; activation and dimerization of Stat5A requires phosphorylation of STATs.
Application: IHC(P), WB, IP
Formulation: This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer
Pulled From: Serum
Specificity: STAT5A
Molecular Wt: 92
Purification: The Rabbit IgG is purified by site-modified Epitope Affinity Purification.
Western Blot: 0.1-1 µg/ml
Concentration: 100ug/200ul
Flow Cytometry: Not tested
Positive Control: GH stimulated mouse liver
Alternative Names: Signal transducer and activator of transcription 5a (STAT5a)
Cellular Location: Nuclear
Species Reactivity: Hu, Ms
Immunoprecipitation: 2-5 µg/ml
Storage Temperature: The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Format (Liquid/Lyophilized): Liquid