Fucokinase Antibody (C-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 197258
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: FCSK
Other Names: L-fucose kinase, Fucokinase, FUK
Availability: 2 weeks
Bio Background: Fucokinase belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis.
Bio References: Clark, H.F., et al., Genome Res. 13(10):2265-2270 (2003).Hinderlich, S., et al., Biochem. Biophys. Res. Commun. 294(3):650-654 (2002).
Other Accession: NP_659496
Primary Accession: Q8N0W3
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP8165b was selected from the C-term region of human Fucokinase. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.