Monoclonal Antibody to TLR8/CD288 FITC Conjugated (Clone: ABM15F6)

DESCRIPTION

Toll like receptor 8, also known as CD288, is a member of TLR family. It plays an important role in sensing phagocytosed pathogen. TLR8 recognizes ssRNA and recruits MyD88 and leads to the activation of transcription factor NF-kappa B. TLR8 TLR8 has two splice variants, viz., TLR8v1 and TLR8v2 and one missense variant, termed G or A1G allele of TLR8. TLR8v1 has additional 19 amino acids in the N-terminus. It is predominantly expressed in lung and peripheral blood leukocytes.

DETAILS

Gene: TLR8
App Id: FACS
Antigen: TLR8/CD288
Gene Id: 51311
Isotype: Mouse IgG1 Kappa
Format Id: Purified
Clone Name: ABM15F6
Uniprot Id: Q9NR97
Host Animal: Mouse
Clonality Id: Monoclonal
Conjugate Id: FITC
Purification: Protein G Chromatography
Reactivity Id: Human
Product Content: 0.2 mg/ml in Tris buffer containing 0.05% Azide
Alternative Name: TLR8||UNQ249/PRO286
Application Note: FACS analysis: 0.5-1 µg/10^6 cells
Categories Name 1: Antibodies
Categories Name 2: TLR and Innate Immunity
Storage Condition: Store the antibody at 4°C, stable for 6 months.
Immunogen Information: A partial length recombinant TLR8 protein (amino acids 750-900) was used as the immunogen for this antibody.