30-1134
Anti-CD54 / ICAM-1 Monoclonal Antibody (Clone:MEM-112)
Abeomics
DESCRIPTION
CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.
DETAILS
- Gene: ICAM1
- App Id: FACS, IP
- Antigen: CD54
- Gene Id: 3383
- Isotype: Mouse IgG1
- Format Id: Purified
- Clone Name: MEM-112
- Uniprot Id: P05362
- Host Animal: Mouse
- Clonality Id: Monoclonal
- Purification: Purified by protein-A affinity chromatography
- Reactivity Id: Human
- Alternative Name: ICAM1
- Application Note: Flow Cytometry Recommended dilution:5 µg/ml Immunoprecipitation
- Storage Condition: Store at 2-8°C. Do not freeze.
- Immunogen Information: Raji Burkitt's lymphoma cell line Raji