T35629
ATRA-BA Hybrid
TargetMol
DESCRIPTION
ATRA-BA hybrid is a mutual prodrug form of all-transretinoic acid and butyric acid .1ATRA-BA hybrid is cleaved to release ATRA and BA in isolated mouse plasma. It inhibits the growth of MDA-MB-231 breast and PC3 prostate cancer cells with GI50values of 0.01 and 1.02 μM, respectively. ATRA-BA (20 μM) has 15-fold greater antiproliferative activity in PC3 cells compared to an equimolar concentration of ATRA and BA.
DETAILS
- Cas: 1037543-26-2
- Purity: 98%
- Smiles: O(C(/C=C(/C=C/C=C(/C=C/C=1C(C)(C)CCCC1C)\C)\C)=O)C2=CC=C(COC(CCC)=O)C=C2
- Category: Compound
- Molecular Weight: 476.65
- Molecular Formula: C31H40O4
Lead Time: Please Inquire
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