DESCRIPTION

• Notes: License Disclosure: Purchase of this cell line grants you with a 10-year license to use this cell line in your immediate laboratory, for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make the cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit use of this cell line in humans or for therapeutic or drug use. The license does not permit modification of the cell line in any way. Inappropriate use or distribution of this cell line will result in revocation of the license and result in an immediate cease of sales and distribution of BPS products to your laboratory. BPS does not warrant the suitability of the cell line for any particular use, and does not accept any liability in connection with the handling or use of the cell line. Modifications of this cell line, transfer to another facility, or commercial use of the cells may require a separate license and additional fees; contact sales@bpsbioscience.com for details. Publications using this cell line should reference BPS Bioscience, Inc., San Diego.
• Shiptemp: -80°C (dry ice)
• Synonyms: Acute-Phase Response Factor, DNA-Binding Protein APRF, DNA, ADMIO, Signal Transducer And Activator Of Transcription 3, TATA
• Category: Cell Line/Cell Signaling Pathway
• References: 1. Tian S., et al., Blood. 1994; 84(6):1760-1764.2. Zhong, Z., et al., Science. 1994; 264(5155):95-98.
• Description: The STAT3 Reporter (Luc)-HEK293 cell line is designed for monitoring STAT3 signal transduction pathway. It contains a firefly luciferase gene driven by STAT3 response elements located upstream of the minimal TATA promoter. After activation by cytokines and growth factors, endogenous STAT3 binds to the DNA response elements, inducing transcription of the luciferase reporter gene.
• Supplied As: Each vial contains ~2 X 10^6 cells in 1 ml of 10% DMSO.
• Unspsc Code: 41106514
• Unspsc Name: Stable mammalian cell lines
• Applications: • Monitor the STAT3 signaling pathway activity • Screen for activators or inhibitors of the STAT3 signaling pathway
• Host Species: human
• Product Type: Cell Line
• Host Cell Line: HEK293
• Biosafety Level: BSL-2
• Related Products: 90196-B, 40449
• Storage Stability: Immediately upon receipt, store in liquid nitrogen.
• Mycoplasma Testing: The cell line has been screened using the PCR-based Venor™ GeM Mycoplasma Detection kit (Sigma-Aldrich, #MP0025) to confirm the absence of Mycoplasma species.
• Scientific Category: Cell Signaling Pathway
• Instructions for Use: See assay protocol for detailed instructions.
• Required Accessories: 60187,79801,79796,60690
• Signed License Required: Yes