Anti-CD41 / Platelet GPIIb Monoclonal Antibody (Clone:MWReg30)-Low Endotoxin

DESCRIPTION

CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.

DETAILS

Gene: Itga2b
App Id: FACS, IP, IHC, IHC-Fr, ELISA, Functional Assay
Antigen: CD41 (mouse)
Gene Id: 16399
Isotype: Rat IgG1
Format Id: Low Endotoxin
Clone Name: MWReg30
Uniprot Id: Q9QUM0
Host Animal: Rat
Clonality Id: Monoclonal
Purification: Purified by protein-G affinity chromatography
Reactivity Id: Mouse
Alternative Name: Itga2b
Application Note: Flow Cytometry Immunoprecipitation Immunohistochemistry Immunohistochemistry (frozen sections) ELISA Functional Application platelet depletion
Storage Condition: Store at 2-8°C. Do not freeze.
Immunogen Information: Murine platelets