35633
Kisspeptin-234 (trifluoroacetate salt)
Cayman Chemical
DESCRIPTION
A peptide kisspeptin receptor antagonist; inhibits kisspeptin-10-induced inositol phosphate production in CHO cells expressing the human kisspeptin receptor (IC50 = 7 nM) and kisspeptin-10-induced firing of isolated mouse GnRH neurons; inhibits pulsatile GnRH secretion in pubertal female rhesus monkeys; inhibits kisspeptin-10-induced luteinizing hormone secretion in adult male rats and mice
DETAILS
- Inchi: InChI=1S/C63H78N18O13.C2HF3O2/c1-34(74-35(2)82)56(88)79-50(29-52(65)84)62(94)80-48(27-39-31-71-43-21-12-10-19-41(39)43)61(93)81-49(28-51(64)83)58(90)73-32-53(85)75-46(25-37-16-7-4-8-17-37)57(89)72-33-54(86)76-47(26-38-30-70-42-20-11-9-18-40(38)42)60(92)77-44(22-13-23-69-63(67)68)59(91)78-45(55(66)87)24-36-14-5-3-6-15-36;3-2(4,5)1(6)7/h3-12,14-21,30-31,34,44-50,70-71H,13,22-29,32-33H2,1-2H3,(H2,64,83)(H2,65,84)(H2,66,87)(H,72,89)(H,73,90)(H,74,82)(H,75,85)(H,76,86)(H,77,92)(H,78,91)(H,79,88)(H,80,94)(H,81,93)(H4,67,68,69);(H,6,7)/t34-,44+,45+,46+,47-,48+,49+,50+;/m1./s1
- Purity: ≥98%
- Raptas: Product Type|Biochemicals|Peptides||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Endocrinology & Metabolism|Hormones & Receptors||Research Area|Neuroscience|Neuroendocrinology
- Smiles: CC(N[C@H](C)C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](CC(N)=O)C(NCC(N[C@H](C(NCC(N[C@@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC1=CC=CC=C1)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O)CC4=CC=CC=C4)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O.O=C(O)C(F)(F)F
- Inchikey: XYUGIYOAGFFAEE-VIJDQBLHSA-N
- Cas Number: 1848962-29-7
- Formulation: A solid
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C63H78N18O13 • XCF3COOH
- Formula Weight: 1295.4
- Shelf Life Days: 1460