DESCRIPTION

• Aa: 2-216
• Mw: 51 kDa
• Tags: N-terminal GST-tag
• Format: Aqueous buffer solution
• Genbank: NM_001968
• Species: Human
• Uniprot: P06730
• Shiptemp: -80°C (dry ice)
• Synonyms: EIF4E1, Eukaryotic Translation Initiation Factor 4E, mRNA Cap-Binding Protein, EIF-4E
• Warnings: Avoid freeze/thaw cycles.
• Category: Kinase/Kinase Substrates
• References: 1. Shih,J.W. et al., Oncogene 27(5), 700-714 (2008). 2. Salehi Z., Mashayekhi F. and Shahosseini F. Cell Biol. Int. 31(11), 1400-1404 (2007). Application Reference: MNK1-induced eIF-4E phosphorylation in myeloma cells: a pathway mediating IL-6-induced expansion and expression of genes involved in metabolic and proteotoxic responses (2014)
• Description: Human eIF4e (eukaryotic translation initiation factor 4E) (GenBank Accession No. NM_001968), a.a. 2-216 with N-terminal GST-tag, MW= 51 kDa, expressed in an E. coli expression system.
• Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 16 mM glutathione
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Suitable substrate for MNK1 kinase and other kinase assays.
• Product Type: Protein
• Biosafety Level: Not applicable (BSL-1)
• Storage Stability: >12 months at -80°C
• Scientific Category: Kinase/Substrate