NBQX disodium salt

DESCRIPTION

NBQX is a potent and selective AMPA and kainate receptor antagonist that is used to counter glutamate excitotoxicity. It is reported to exhibit anticonvulsant activity in rodent models. NBQX disodium salt is the more water soluble version of this reagent.

DETAILS

Purity: ≥98%
Synonyms: 1,2,3,4-Tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide disodium salt, FG9202 disodium
Cas Number: 479347-86-9
References: Chapman, A. G., Smith, S. E., & Meldrum, B. S. (1991). The anticonvulsant effect of the non-NMDA antagonists, NBQX and GYKI 52466, in mice.Epilepsy research, 9(2), 92-96. Gill, R., Nordholm, L., & Lodge, D. (1992). The neuroprotective actions of 2, 3-dihydroxy-6-nitro-7-sulfamoyl-benzo (F) quinoxaline (NBQX) in a rat focal ischaemia model. Brain research, 580(1), 35-43. Wrathall, J. R., Choiniere, D., & Teng, Y. D. (1994). Dose-dependent reduction of tissue loss and functional impairment after spinal cord trauma with the AMPA/kainate antagonist NBQX. The Journal of neuroscience,14(11), 6598-6607.
Application: FA
Formulation: Crystalline solid
Chemical Name: disodium;6-nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-diolate
Molecular Weight: 380.2
Molecular Formula: C12H6N4O6S 2Na
Storage Conditions: Product should be kept at -20°C.
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