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38282

YK-009

Cayman Chemical

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DETAILS

  • Inchi: InChI=1S/C40H79NO5/c1-4-7-10-13-16-17-20-26-36-45-39(43)31-27-33-41(34-35-42)32-25-21-24-30-40(44)46-37-38(28-22-18-14-11-8-5-2)29-23-19-15-12-9-6-3/h38,42H,4-37H2,1-3H3
  • Purity: ≥95%
  • Raptas: Product Type|Biochemicals|Lipids||Research Area|Cardiovascular System|Blood|Serum Proteins||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Pulmonary Diseases|COVID-19||Research Area|Infectious Disease|Viral Diseases|Coronaviruses||Research Area|Lipid-Based Drug Delivery|Cationic Lipids (Ionizable)|Branched Tail||Research Area|Lipid-Based Drug Delivery|Cationic Lipids (Ionizable)|Multi-Tail Non-Disulfide
  • Smiles: OCCN(CCCCCC(OCC(CCCCCCCC)CCCCCCCC)=O)CCCC(OCCCCCCCCCC)=O
  • Inchikey: QXJDKBITLMHUSD-UHFFFAOYSA-N
  • Cas Number: 2761458-86-8
  • Formulation: A solution in ethanol
  • Storage Temp: -20
  • Shipping Temp: -20
  • Formula Markup: C40H79NO5
  • Formula Weight: 654.1
  • Shelf Life Days: 1095

DESCRIPTION

An ionizable cationic lipid (pKa = 6.512); administration of SARS-CoV-2 Omicron variant mRNA in YK009-containing LNPs induces SARS-CoV-2 RBD-binding IgG in mice, with a boost in antigen-specific IgG titers 10 days after a second dose