YK-009

DESCRIPTION

An ionizable cationic lipid (pKa = 6.512); administration of SARS-CoV-2 Omicron variant mRNA in YK009-containing LNPs induces SARS-CoV-2 RBD-binding IgG in mice, with a boost in antigen-specific IgG titers 10 days after a second dose

DETAILS

Inchi: InChI=1S/C40H79NO5/c1-4-7-10-13-16-17-20-26-36-45-39(43)31-27-33-41(34-35-42)32-25-21-24-30-40(44)46-37-38(28-22-18-14-11-8-5-2)29-23-19-15-12-9-6-3/h38,42H,4-37H2,1-3H3
Purity: ≥95%
Raptas: Product Type|Biochemicals|Lipids||Research Area|Cardiovascular System|Blood|Serum Proteins||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Pulmonary Diseases|COVID-19||Research Area|Infectious Disease|Viral Diseases|Coronaviruses||Research Area|Lipid-Based Drug Delivery|Cationic Lipids (Ionizable)|Branched Tail||Research Area|Lipid-Based Drug Delivery|Cationic Lipids (Ionizable)|Multi-Tail Non-Disulfide
Smiles: OCCN(CCCCCC(OCC(CCCCCCCC)CCCCCCCC)=O)CCCC(OCCCCCCCCCC)=O
Inchikey: QXJDKBITLMHUSD-UHFFFAOYSA-N
Cas Number: 2761458-86-8
Formulation: A solution in ethanol
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C40H79NO5
Formula Weight: 654.1
Shelf Life Days: 1095