IT7-M53W3-50ug IT7-M53W3-1mg
Mouse Integrin alpha E beta 7 (ITGAE&ITGB7) Heterodimer Protein, His Tag&Tag Free
ACROBiosystems
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DESCRIPTION
Integrin alpha E beta 7 consist of two major subunits: Integrin alpha E (ITGAE) also known as CD103 (cluster of differentiation 103) and Integrin beta-7 is an integrin protein that in humans is encoded by the ITGB7 gene. Integrin alpha E beta 7 (CD103) is expressed mainly by cells of the T lymphocyte lineage within mucosal tissues. This is a strikingly narrow pattern of expression compared with that of other integrins. Lymphocytes expressing alpha E beta 7 are abundant in the gut and comprise a major part of the total T cell complement of the body.
The effectiveness of lung transplantation is marred by the relatively high incidence of rejection. The lung normally contains a large population of lymphocytes in contact with the airway epithelium, a proportion of which expresses the mucosal integrin, alpha(E)(CD103)beta(7). This integrin is not a homing receptor, but is thought to retain lymphocytes at the epithelial surface.
DETAILS
- Tag: C-10×His | Native
- Host: CHO
- Size: 1mg
- Buffer: 50 mM Tris, 150 mM NaCl, pH 7.5
- Format: Powder
- Purity: 90%
- Source: Mouse ITGAE&ITGB7 Heterodimer Protein, His Tag&Tag Free (IT7-M53W3) is expressed from CHO cells. It contains AA Phe 20- Val 1114 & Glu 20 - Arg 724 (Accession # Q60677 & P26011).
- Storage: -20℃
- Category: Bio-Markers & CD Antigens
- Molecule: Integrin alpha E beta 7
- Conjugate: Biotin-labeled
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Phe 20- Val 1114 & Glu 20 - Arg 724
- Swiss-prot: Q60677 | P26011
- Package Size: 500ug*2
- Characteristics: The protein has a calculated MW of 127.5 kDa & 81.6 kDa. The protein migrates as 90-95 kDa,130 kDa and 150 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 127.5 kDa & 81.6 kDa
- Shipping Condition: RT
- Species Reactivity: Mouse
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html