GSK3β Assay Kit

DESCRIPTION

The GSK3β Assay Kit is designed to measure GSK3β activity for screening and profiling applications using Kinase-Glo® (Promega) as a detection reagent.

DETAILS

Shiptemp: -80°C (dry ice)
Synonyms: Glycogen Synthase Kinase 3 Beta, GSK-3 Beta, Serine/Threonine-Protein Kinase GSK3B
Warnings: Avoid multiple freeze/thaw cycles.
Category: Kinase/Assay Kit
Background: GSK3 (Glycogen synthase kinase) is a serine/threonine kinase which initially was found to phosphorylate and inactivate glycogen synthase in glycogen biosynthesis. It is an important regulator enzyme in many disease pathogeneses including cancer, immune disorders, metabolic disorders and neurological disorders like Alzheimer's disease. In fact, GSK3β, one of the isoforms of GSK3, was identified as a key regulator in tau-driven Alzheimer's disease.
References: McCubrey JA., et al. Oncotarget 5(10): 2881-2911 (2014)
Description: The GSK3β Assay Kit is designed to measure GSK3β activity for screening and profiling applications using Kinase-Glo® (Promega) as a detection reagent.
Methodology: Chemiluminescent
Unspsc Code: 41105332
Unspsc Name: Protein chemiluminescent detection reagents or kits or substrates
Product Type: Assay Kit
Biosafety Level: Not applicable (BSL-1)
Related Products: 40006, 40007, 79698, 78487
Contraindications: Keep final DMSO concentration below 1%
Storage Stability: Up to 6 months when stored as recommended.
Scientific Category: Kinase
Instructions for Use: See assay protocol.