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Recombinant Human LAG-1 (CCL4L1)



LAG-1 is CC chemokine that signals through the CCR5 receptor. LAG-1 is identical to MIP-1beta (ACT II isotype) except for two amino acid substitutions; arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV-suppressive factor. Recombinant Human LAG-1 is a 7.7 kDa protein containing 69 amino acid residues.


  • Gene Id: 388372
  • Uniprot: Q8NHW4
  • Activity: Determined by its ability to chemoattract CCR5-transfected cells using a concentration of 0.1-10.0 ng/ml
  • Category: RUO Cytokines
  • Subcategory: Chemokines
  • Research Areas: AIDS/HIV, Chemotaxis, Immune System, Wound Healing
  • Alternative Names: Lymphocyte Activation Gene-1, CCL4L1, ACT-2, T-cell activiation-2, HC21
  • Species of Origin: Human
  • Expression System Source: E.coli