Leucomycin A13

DESCRIPTION

A macrolide antibiotic; active against B. subtilis, S. aureus, M. luteus, and E. coli (MICs = 0.16, 0.16, 0.08 and >10 µg/ml, respectively); binds to ribosomes (IC50 = 1.2 µM)

DETAILS

Inchi: InChI=1S/C41H69NO14/c1-10-11-13-18-31(46)54-39-27(5)52-33(23-41(39,6)49)55-36-26(4)53-40(35(48)34(36)42(7)8)56-37-28(19-20-43)21-24(2)29(44)17-15-12-14-16-25(3)51-32(47)22-30(45)38(37)50-9/h12,14-15,17,20,24-30,33-40,44-45,48-49H,10-11,13,16,18-19,21-23H2,1-9H3/b14-12+,17-15+/t24-,25-,26-,27+,28+,29+,30-,33+,34-,35-,36-,37+,38+,39+,40+,41-/m1/s1
Purity: ≥99%
Raptas: Product Type|Biochemicals|Antibiotics|Macrolides||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases
Smiles: O[C@H]1[C@H](OC)[C@@H](O[C@]2([H])O[C@H](C)[C@@H](O[C@@]3([H])C[C@](O)(C)[C@@H](OC(CCCCC)=O)[C@H](C)O3)[C@H](N(C)C)[C@H]2O)[C@@H](CC=O)C[C@@H](C)[C@@H](O)/C=C/C=C/C[C@@H](C)OC(C1)=O
Inchikey: CUDHGRIZNLIHBG-TYBIZVFLSA-N
Cas Number: 78897-52-6
Formulation: A solid
Item Origin: Bacterium/Streptomyces kitasatoensis
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C41H69NO14
Formula Weight: 800
Shelf Life Days: 1460