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T14298

Rimiducid

TargetMol

- Open Babel Depiction O CH 3 O N O CH 3 O CH 3 O CH 3 O CH 3 O CH 3 O CH 3 O CH 3 O CH 3 O O H 3 C O CH 3 O O N O O O N H CH 3 N H O O

DESCRIPTION

Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wild-type fkbp12 with 1000-fold lower affinity. Rimiducid is a dimerizer agent that acts by cross-linking the FKBP domains. It dimerizes the Caspase 9 suicide switch and rapidly induces apoptosis.

DETAILS

  • Cas: 195514-63-7
  • Purity: 98%
  • Smiles: [C@H](C(=O)N1[C@H](C(O[C@H](CCC2=CC(OC)=C(OC)C=C2)C3=CC(OCC(NCCNC(COC4=CC([C@H](OC(=O)[C@H]5N(C([C@@H](CC)C6=CC(OC)=C(OC)C(OC)=C6)=O)CCCC5)CCC7=CC(OC)=C(OC)C=C7)=CC=C4)=O)=O)=CC=C3)=O)CCCC1)(CC)C8=CC(OC)=C(OC)C(OC)=C8
  • Category: Compound
  • Molecular Weight: 1411.63
  • Molecular Formula: C78H98N4O20

Lead Time: 4 - 5 weeks

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