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ILA-H5219-25ug ILA-H5219-100ug ILA-H5219-1mg

Human IL-17A / CTLA-8 Protein, premium grade

ACROBiosystems

DESCRIPTION

Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

DETAILS

  • Tag: Native
  • Host: HEK293
  • Size: 25ug
  • Buffer: PBS, pH7.4
  • Format: Powder
  • Purity: 90%
  • Source: Human IL17A, premium grade (ILA-H5219) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Ala 155 (Accession # Q16552-1).
  • Storage: -20℃
  • Category: Cytokines&Growth Factors
  • Molecule: IL-17A
  • Accession: NP_002181.1
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Exp Region: Gly 24 - Ala 155
  • Swiss-prot: Q16552-1
  • Package Size: 25ug*1
  • Characteristics: This protein carries no "tag". The protein has a calculated MW of 15.1 kDa. The protein migrates as 16 kDa, 17 kDa and 19 kDa under reducing (R) condition, and 27-34 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 0.1 EU per μg
  • Molecular Weight: 15.1 kDa
  • Shipping Condition: RT
  • Species Reactivity: Human
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html