Dextran Size: 40 kDa Fluorescent Dye Label: AFDye 647 Volume (@ 5 mg/mL Fe): 1 mL General Information Fluorescent, Biotin functionalized Dextran coated crosslinked iron oxide nanoparticles (CLIO-BIOTD) have 1-3 superparamagnetic Fe3O4 iron oxide cores (8-10 nm in diameter) imbedded within the matrix of dextran strands of 40 or 70 kDa in size. Dextran strands are crosslinked to prevent their disassociation, ensuring long-term stability. Biotin and fluorescence dye are covalently conjugated to the nanoparticle surface. Features: Superparamagnetic Fluorescently labeled (AFDye 488, AFDye 555, AFDye 647, or IR750 dye) Highly biocompatible, non-toxic Long term stable under physiological conditions 40 kDa and 70 kDa dextran coats are available Easy loading of biomolecules such as Antibodies through Streptavidin-Biotin interaction Applications: In vitro and in vivo dual magnetic and fluorescence labels for cells and tissues. Magnetic, fluorescence, or dual cell separation. Probes for MRI. Specifications: Iron Oxide Core Diameter: 8 – 10 nm Hydrodynamic Diameter: 50 – 110 nm Polydispersity Index (PDI): < 0.3 Magnetization: 5 – 30 emu/g (room temperature) Fluorescent Dye: AFDye 488 (AlexaFluor 488 analog, Abs/Em = 490/525, Filter set: FITC) AFDye 555 (AlexaFluor 555 analog, Abs/Em = 555/580, Filter set: TRITC) AFDye 647 (AlexaFluor 647 analog, Abs/Em = 650/665, Filter set: Cy5) IR750 (IRDye 750 analog, Abs/Em = 756/776, Filter set: Cy7) Shelf life: > 1 year (4°C storage)