12-9256-B
Biotinylated Anti-TIM3 antibody(DM82), Rabbit mAb
Abeomics
DESCRIPTION
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
DETAILS
- App Id: ELISA, FACS
- Antigen: TIM3
- Format Id: Liquid
- Clone Name: DM82
- Host Animal: Rabbit
- Clonality Id: Monoclonal
- Purification: Purified from cell culture supernatant by affinity chromatography
- Reactivity Id: Human
- Alternative Name: HAVCR2, TIM-3, TIMD3, FLJ14428, KIM3,KIM-3
- Application Note: ELISA 1/5000-10000;FACS 1/100
- Storage Condition: Store at 2 °C-8 °C for 6 months