Influenza A [Wisconsin/588/2019(H1N1)] Neuraminidase (NA) Protein, His Tag

DESCRIPTION

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

DETAILS

Tag: N-10×His
Host: HEK293
Size: 1mg
Buffer: 50 mM Tris, 300 mM NaCl, pH 7.5
Format: Liquid
Purity: 90%
Source: Influenza A [Wisconsin/588/2019(H1N1)] Neuraminidase (NA) Protein, His Tag (NEE-V524k) is expressed from human 293 cells (HEK293). It contains AA Val 80 - Lys 469 (Accession # EPI_ISL_404527, GISAID).
Storage: -70℃
Category: Viral Proteins
Molecule: Neuraminidase (NA)
Conjugate: Unconjugated
Stability: ● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Exp Region: Val 80 - Lys 469
Swiss-prot: EPI_ISL_404527
Package Size: 1mg*1
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 50.8 kDa. The protein migrates as 60-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 50.8 kDa
Shipping Condition: Dry ice
Species Reactivity: Influenza
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