KL1-C5243-100ug KL1-C5243-1mg
Cynomolgus KLRG1 Protein, His Tag (SPR verified)
ACROBiosystems
DESCRIPTION
The co-inhibitory receptor killer-cell lectin like receptor G1 (KLRG1) is specifically expressed on NK cells and activated CD8+ T-cells and has been postulated to be a marker of senescence. KLRG1+ T cells are a major reason of chronic tissue damage in some autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. In tumors, tumor cells which express E-cadherin or N-cadherin bind to KLRG1 and inhibit the antitumor activity of T and NK cells. Thus, KLRG1 acts as an immunocheckpoint inhibitory receptor.
DETAILS
- Tag: N-10×His
- Host: HEK293
- Size: 1mg
- Buffer: PBS, pH7.4
- Format: Powder
- Purity: 90%
- Source: Cynomolgus KLRG1 Protein, His Tag (KL1-C5243) is expressed from human 293 cells (HEK293). It contains AA Leu 60 - Pro 189 (Accession # A0A2K5WAP9).
- Storage: -20℃
- Category: Other Recombinant Proteins
- Molecule: KLRG1
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Leu 60 - Pro 189
- Swiss-prot: A0A2K5WAP9
- Package Size: 500ug*2
- Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 16.8 kDa. The protein migrates as 18-21 kDa and 22-30 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 16.8 kDa
- Shipping Condition: RT
- Species Reactivity: Cynomolgus
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html