PE-Labeled Human HLA-A*02:01&B2M&KRASG12V (KLVVVGAVGV) Tetramer Protein

DESCRIPTION

The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Human HLA-A*0201 KRASG12V (KLVVVGAVGV) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and KLVVVGAVGV peptide of the KRASG12V.

DETAILS

Tag: C-10×His
Host: HEK293
Size: 25ug
Buffer: PBS, 1% BSA, pH7.4
Format: Powder
Purity: 90%
Source: PE-Labeled Human HLA-A*02:01&B2M&KRASG12V (KLVVVGAVGV) Tetramer Protein (HLV-HP2H6) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & KLVVVGAVGV peptide (Accession # AAA59606.1 (HLA-A*02:01) & P61769-1 (B2M) & KLVVVGAVGV).
Storage: -20℃, aviod light
Category: Fluorescent labeled protein
Molecule: HLA-A*0201 & B2M & KRASG12V (KLVVVGAVGV)
Conjugate: PE Labeled
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & KLVVVGAVGV peptide
Swiss-prot: AAA59606.1 & P61769-1 & KLVVVGAVGV
Package Size: 25ug*1
Characteristics: PE-Labeled Human HLA-A*02:01&B2M&KRASG12V (KLVVVGAVGV) Tetramer Protein is assembled by biotinylated monomer (HLV-H82E3) and PE-labeled streptavidin. Biotinylated Human HLA-A*02:01&B2M&KRASG12V (KLVVVGAVGV) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12V peptide. Biotinylated Human HLA-A*02:01&B2M&KRASG12V (KLVVVGAVGV) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 36.3 kDa and 11.7 kDa
Shipping Condition: RT
Species Reactivity: Human
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