Human MMP-8 Protein, His Tag (active enzyme)

DESCRIPTION

Matrix metalloproteinase-8（MMP-8）also known as neutrophil collagenase and CLG1，is a member of matrix metalloproteinases (MMPs) family，which degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes as well as pathological processes. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 in the tumor may have a protective effect against lymph node metastasis.

DETAILS

Tag: C-10×His
Host: HEK293
Size: 1mg
Buffer: 50 mM Tris,150 mM NaCl,pH8.0
Format: Liquid
Purity: 90%
Source: Human MMP-8 Protein, His Tag (MM8-H52H7) is expressed from human 293 cells (HEK293). It contains AA Phe 21 - Gly 262 (Accession # P22894-1). It needs to be activated by agents such as APMA in vitro to have hydrolytic activity.
Storage: -70℃
Category: Enzymes
Molecule: MMP-8
Conjugate: Unconjugated
Stability: ● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Exp Region: Phe 21 - Gly 262
Swiss-prot: P22894-1
Package Size: 1mg*1
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 29.0 kDa. The protein migrates as 38-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 29.0 kDa
Shipping Condition: Dry ice
Species Reactivity: Human
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