FTO, His-Tag Recombinant

DESCRIPTION

Human FTO, also known as Fat mass and obesity-associated protein, ALKBH9; BMIQ14; GDFD; KIAA1752, and alpha-ketoglutarate-dependent dioxygenase, GenBank Accession No. NM_001080432, a.a 32-505 (end), with N-terminal His-Tag and expressed in a E. coli cell expression system. MW = 56 kDa.

DETAILS

Aa: 32-505
Mw: 56 kDa
Tags: N-Terminal His-Tag
Format: Aqueous buffer solution
Genbank: NM_001080432
Species: Human
Uniprot: Q9C0B1
Shiptemp: -80°C (dry ice)
Synonyms: Fat mass and obesity-associated protein, ALKBH9; BMIQ14; GDFD; KIAA1752, and alpha-ketoglutarate-dependent dioxygenase
Warnings: Avoid freeze/thaw cycles. Storing diluted enzyme is not recommended, if necessary, use carrier protein (BSA 0.1 - 0.5%).
Category: Demethylase/Enzymes
References: 1. Frayling, T., et al., Science. 2007; 316(5826): 889-894.2. Dina, C., et al., Nature Genetics. 2007; 39(6): 724-726.
Description: Human FTO, also known as Fat mass and obesity-associated protein, ALKBH9; BMIQ14; GDFD; KIAA1752, and alpha-ketoglutarate-dependent dioxygenase, GenBank Accession No. NM_001080432, a.a 32-505 (end), with N-terminal His-Tag and expressed in a E. coli cell expression system. MW = 56 kDa.
Formulation: 40 mM Tris-HCl pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT and 20% glycerol.
Unspsc Code: 12352202
Unspsc Name: Proteins
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Product Type: Protein
Biosafety Level: Not applicable (BSL-1)
Related Products: 79344, 79480
Storage Stability: At least 6 months at -80°C.
Scientific Category: DNA Demethylase