Rat GITR / TNFRSF18 Protein, His Tag

DESCRIPTION

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

DETAILS

Tag: C-8×His
Host: HEK293
Size: 1mg
Buffer: PBS, pH7.4
Format: Powder
Purity: 95%
Source: Rat GITR, His Tag (GIR-R5222) is expressed from human 293 cells (HEK293). It contains AA Gln 20 - Lys 121 (Accession # Q5M835).
Storage: -20℃
Category: Immune Checkpoint Proteins
Molecule: GITR
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Gln 20 - Lys 121
Swiss-prot: Q5M835
Package Size: 250ug*4
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 12.3 kDa. The protein migrates as 21 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 12.3 kDa
Shipping Condition: RT
Species Reactivity: Rat
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