Cynomolgus CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag (MALS verified)

DESCRIPTION

T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

DETAILS

Tag: C-Fc | C-Fc
Host: HEK293
Size: 100ug
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
Format: Powder
Purity: 95%
Source: Cynomolgus CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag (CDG-C5257) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Asp 117 (CD3E) & Gln 23 - Thr 113 (CD3G) (Accession # Q95LI5-1 (CD3E) & Q95LI7-1 (CD3G)).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: CD3E & CD3G
Accession: NP_001270544.1 (CD3E) & NP_001270839.1 (CD3G)
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Gln 22 - Asp 117 (CD3E) & Gln 23 - Thr 113 (CD3G)
Swiss-prot: Q95LI5-1 (CD3E) & Q95LI7-1 (CD3G)
Package Size: 100ug*1
Characteristics: Cynomolgus CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag is produced by co-expression of CD3E and CD3G, has a calculated MW of 40.6 kDa (CD3E) and 40.4 kDa (CD3G). Subunit CD3E is fused with a human IgG1 Fc tag at the C-terminus and subunit CD3G is fused with a human IgG1 Fc tag at the C-terminus. The reducing (R) heterodimer protein migrates as 45-52 kDa due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 40.6 kDa (CD3E) & 40.4 kDa (CD3G)
Shipping Condition: RT
Species Reactivity: Cynomolgus
Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html