Mouse PTK7 / CCK4 Protein, Fc Tag (MALS verified)

DESCRIPTION

PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.

DETAILS

Tag: C-Fc
Host: HEK293
Size: 1mg
Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Format: Powder
Purity: 90%
Source: Mouse PTK7 Protein, Fc Tag (PT7-M5256) is expressed from human 293 cells (HEK293). It contains AA Ala 23 - Thr 696 (Accession # Q8BKG3-1).
Storage: -20℃
Category: Enzymes
Molecule: PTK7
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ala 23 - Thr 696
Swiss-prot: Q8BKG3-1
Package Size: 500ug*2
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 101.0 kDa. The protein migrates as 130-150 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 101.0 kDa
Shipping Condition: RT
Species Reactivity: Mouse
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