Human CCL3 / MIP-1 alpha Protein, His Tag

DESCRIPTION

CCL3, also know as MIP-1-alpha, is monokine with inflammatory and chemokinetic properties. CCL3 is an important chemokine implicated in both immune surveillance and tolerance, has emerged as a prognostic biomarker in both solid and hematological malignancies. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

DETAILS

Tag: N-10×His
Host: E. coli
Size: 1mg
Buffer: 20 mM Tris,150 mM NaCl,0.2 M Arginine,1 mM EDTA,pH8.0
Format: Powder
Purity: 95%
Source: Human CCL3, His Tag (CC3-H5249) is expressed from E. coli cells. It contains AA Ser 24 - Ala 92 (Accession # P10147-1).
Storage: -20℃
Category: Cytokines&Growth Factors
Molecule: CCL3
Accession: NP_002974.1
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ser 24 - Ala 92
Swiss-prot: P10147-1
Package Size: 500ug*2
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 9.7 kDa. The protein migrates as 12-13 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level: 0.1 EU per μg
Molecular Weight: 9.7 kDa
Shipping Condition: RT
Species Reactivity: Human
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