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E0209Hu

Human E-Cadherin, E-CAD ELISA Kit

Bioassay Technology Laboratory

DESCRIPTION

Cadherins are calcium-dependent cell adhesion proteins (PubMed: 11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed: 11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production. (Microbial infection) Serves as a receptor for Listeria monocytogenes; internalin A (InlA) binds to this protein and promotes uptake of the bacteria.

DETAILS

  • GeneID: 999
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 97,456
  • Synonyms: Cadherin-1;CAM 120/80;CD antigen CD324;CDH 1;CDH1;E-Cad/CTF1;E-Cad/CTF2;E-Cad/CTF3;E-cadherin;Epithelial cadherin;Uvomorulin
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: CDH1
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 0.52ng/ml
  • Target Protein: CDH1
  • Detection Range: 1-300ng/ml
  • Full Product Name: E-Cadherin
  • Standard Solution: 400ng/ml
  • UniProt Accession: P12830