E1743Hu
Human Pachytene Checkpoint Protein 2 Homolog, TRIP13 ELISA Kit
Bioassay Technology Laboratory
DESCRIPTION
Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity). Plays a role in mitotic spindle assembly checkpoint (SAC) activation (PubMed: 28553959).
DETAILS
- GeneID: 9319
- Species: Human
- Storage: 2-8ºC
- MASS(Da): 48,551
- Synonyms: 16E1-BP;HPV16 E1 protein-binding protein;Human papillomavirus type 16 E1 protein-binding protein;Pachytene checkpoint protein 2 homolog;Thyroid hormone receptor interactor 13;Thyroid receptor-interacting protein 13;TR-interacting protein 13;TRIP 13;TRIP13;TRIP-13
- Assay Time: 1h 30m
- Assay Type: Sandwich
- Gene Names: TRIP13
- Reactivity: Human
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 5.91ng/L
- Target Protein: TRIP13
- Detection Range: 10-2000ng/L
- Full Product Name: Pachytene Checkpoint Protein 2 Homolog
- Standard Solution: 2400ng/L
- UniProt Accession: Q15645