CAD-H52H3-50ug CAD-H52H3-1mg
Human Cathepsin D Protein, His Tag (active enzyme, MALS verified)
ACROBiosystems
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DESCRIPTION
This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]
DETAILS
- Tag: C-10×His
- Host: HEK293
- Size: 1mg
- Buffer: 12.5 mM MES, 75 mM NaCl, pH6.5
- Format: Liquid
- Purity: 95%
- Source: Human Cathepsin D Protein, His Tag (CAD-H52H3) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - Leu 412 (Accession # P07339-1).
- Storage: -70℃
- Category: Enzymes
- Molecule: Cathepsin D
- Conjugate: Unconjugated
- Stability: ● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
- Exp Region: Leu 21 - Leu 412
- Swiss-prot: P07339-1
- Package Size: 1mg*1
- Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 44.5 kDa. The protein migrates as 45-50 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 44.5 kDa
- Shipping Condition: Dry ice
- Species Reactivity: Human
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html