Human Cathepsin D Protein, His Tag (active enzyme, MALS verified)

DESCRIPTION

This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]

DETAILS

Tag: C-10×His
Host: HEK293
Size: 1mg
Buffer: 12.5 mM MES, 75 mM NaCl, pH6.5
Format: Liquid
Purity: 95%
Source: Human Cathepsin D Protein, His Tag (CAD-H52H3) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - Leu 412 (Accession # P07339-1).
Storage: -70℃
Category: Enzymes
Molecule: Cathepsin D
Conjugate: Unconjugated
Stability: ● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Exp Region: Leu 21 - Leu 412
Swiss-prot: P07339-1
Package Size: 1mg*1
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 44.5 kDa. The protein migrates as 45-50 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 44.5 kDa
Shipping Condition: Dry ice
Species Reactivity: Human
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