Kainic Acid Monohydrate

DESCRIPTION

Kainic acid is a potent neuroexcitatory amino acid that acts as a neurotoxin in high doses. It was originally isolated from seaweed and is used in the study of the physiological effect of excitotoxicity and assess the neuroprotective capabilities of potential therapeutics.

DETAILS

Purity: ≥98%
Synonyms: Digenin, Kainic acid hydrate
Cas Number: 58002-62-3
References: Coyle, J. T., & Schwarcz, R. (1976). Lesion of striatal neurons with kainic acid provides a model for Huntington's chorea. Lothman, E. W., & Collins, R. C. (1981). Kainic acid induced limbic seizures: metabolic, behavioral, electroencephalographic and neuropathological correlates. Brain research, 218(1), 299-318. Olney, J. W., Rhee, V., & Ho, O. L. (1974). Kainic acid: a powerful neurotoxic analogue of glutamate. Brain research, 77(3), 507-512.
Application: FA
Formulation: Crystalline solid
Chemical Name: (2S,3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-ylpyrrolidine-2-carboxylic acid;hydrate
Molecular Weight: 231.2
Molecular Formula: C10H15NO4 H2O
Storage Conditions: Product should be kept at -20°C.
Pubchem Openeye Can Smiles: CC(=C)C1CNC(C1CC(=O)O)C(=O)O.O