30-2509
Anti-Mouse LPAM-1 Azide Free Antibody (Clone : DATK32)
Abeomics
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DESCRIPTION
Integrin alpha 4 / beta 7 (CD49d / Ly69) , also known as LPAM-1 (Lymphocyte Peyer´s patch adhesion molecule 1), is a heterodimeric (150 kDa / 130 kDa) integrin complex which mediates lymphocyte homing to Peyer´s patch high endothelial venules and to the intestinal lamina propria. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. Ligands of LPAM-1 are MAdCAM-1, VCAM-1, and fibronectin, but the alpha 4 subunit (CD49d) can mediate also homotypic adhesion.
Specificity : The rat monoclonal antibody DATK32 recognizes an extracellular epitope of integrin alpha 4 (CD49d) and integrin beta7 (Ly69) components of mouse LPAM-1 complex, which is expressed on the majority of peripheral lymphocytes, as well as on subsets of thymocytes and bone marrow cells.
DETAILS
- Gene: Itgb7
- App Id: Functional Assay
- Antigen: LPAM-1
- Gene Id: 16421
- Isotype: Rat IgG2a kappa
- Format Id: Azide Free
- Clone Name: DATK32
- Clonality Id: Monoclonal
- Purification: Purified by protein-A affinity chromatography
- Reactivity Id: Mouse
- Product Content: 1 mg/mlFormulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide
- Alternative Name: Integrin alpha 4 beta 7, CD49d / Ly69
- Storage Condition: Store at 2-8°C. Do not freeze.
- Immunogen Information: TK1 cells
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