sc-514338 SAMPLE sc-514338
Promo Available
Scientist.com Supplier
PRP19 (G-7)
Santa Cruz Biotechnology
Image

DESCRIPTION
mouse monoclonal IgG2a; PRP19 Antibody (G-7) is an IgG2a κ mouse monoclonal PRP19 antibody (also designated PRP19 antibody) that detects the PRP19 protein of mouse, rat and human origin by WB, IP, IF and ELISA. PRP19 Antibody (G-7) is available as both the non-conjugated anti-PRP19 antibody form, as well as multiple conjugated forms of anti-PRP19 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The spliceosome, the gigantic molecular machine that performs pre-mRNA splicing in eukaryotes, contains over 200 different proteins and five RNA molecules (U1, U2, U4, U5 and U6). Pre-mRNA splicing is essential to remove internal non-coding regions of pre-mRNA (introns) and to join the remaining segments (exons) into mRNA before translation. The PRP19-associated complex is required for stable association of U5 and U6 with the spliceosome after U4 is released. Changes within the spliceosome upon binding of the PRP19-associated complex include remodeling of the U6/5' splice site interaction and destabilization of Lsm proteins to allow further interaction of U6 with the intron sequence.
DETAILS
- Host: mouse
- Type: Primary
- Uniprot: Q9UMS4
- Clonality: Monoclonal
- Conjugate: unconjugated
- Applications: WB, IP, IF, ELISA
- Human Gene Id: 27339
- Mouse Gene Id: 28000
- Protein Target: PRP19
- Human Gene Name: PRPF19
- Mouse Gene Name: Prpf19
- Species Reactivity: mouse, rat, human
PROMOTION TERMS
Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.
Equivalent Items
| ... Loading