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sc-514338 SAMPLE sc-514338

Promo Available Scientist.com Supplier

PRP19 (G-7)

Santa Cruz Biotechnology

DESCRIPTION

mouse monoclonal IgG2a; PRP19 Antibody (G-7) is an IgG2a κ mouse monoclonal PRP19 antibody (also designated PRP19 antibody) that detects the PRP19 protein of mouse, rat and human origin by WB, IP, IF and ELISA. PRP19 Antibody (G-7) is available as both the non-conjugated anti-PRP19 antibody form, as well as multiple conjugated forms of anti-PRP19 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The spliceosome, the gigantic molecular machine that performs pre-mRNA splicing in eukaryotes, contains over 200 different proteins and five RNA molecules (U1, U2, U4, U5 and U6). Pre-mRNA splicing is essential to remove internal non-coding regions of pre-mRNA (introns) and to join the remaining segments (exons) into mRNA before translation. The PRP19-associated complex is required for stable association of U5 and U6 with the spliceosome after U4 is released. Changes within the spliceosome upon binding of the PRP19-associated complex include remodeling of the U6/5' splice site interaction and destabilization of Lsm proteins to allow further interaction of U6 with the intron sequence.

DETAILS

  • Host: mouse
  • Type: Primary
  • Uniprot: Q9UMS4
  • Clonality: Monoclonal
  • Conjugate: unconjugated
  • Applications: WB, IP, IF, ELISA
  • Human Gene Id: 27339
  • Mouse Gene Id: 28000
  • Protein Target: PRP19
  • Human Gene Name: PRPF19
  • Mouse Gene Name: Prpf19
  • Species Reactivity: mouse, rat, human

PROMOTION TERMS

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.