HLS-H52H7-25ug HLS-H52H7-200ug
Human HLA-A*03:01&B2M&KRAS (VVVGAGGVGK) Complex Protein (Monomer, MALS verified)
ACROBiosystems
DESCRIPTION
The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Biotinylated Human HLA-A*0301 KRAS (VVVGAGGVGK) complex protein is a complex of HLA-A*0301 of the MHC Class I, B2M, and VVVGAGGVGK peptide of the KRAS.
DETAILS
- Tag: C-10×His
- Host: HEK293
- Size: 25ug
- Buffer: PBS, pH7.4
- Format: Powder
- Purity: 90%
- Source: Human HLA-A*03:01&B2M&KRAS (VVVGAGGVGK) Complex Protein (HLS-H52H7) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*03:01) & Ile 21 - Met 119 (B2M) & VVVGAGGVGK peptide (Accession # P04439 (HLA-A*03:01) & P61769 (B2M) & VVVGAGGVGK).
- Storage: -20℃
- Category: Other Recombinant Proteins
- Molecule: HLA-A*0301 & B2M & KRAS (VVVGAGGVGK)
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Gly 25 - Thr 305 (HLA-A*03:01) & Ile 21 - Met 119 (B2M) & VVVGAGGVGK peptide
- Package Size: 25ug*1
- Characteristics: Human HLA-A*03:01&B2M&KRAS (VVVGAGGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRAS peptide. This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.7 kDa and 15.7 kDa. The protein migrates as 42-45 kDa and 15 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 37.7 kDa and 15.7 kDa
- Shipping Condition: RT
- Species Reactivity: Human
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