Human latent GDF-8 Protein, His Tag (MALS verified)

DESCRIPTION

Growth differentiation factor 8 (GDF8), also known as myostatin, is a unique member of the transforming growth factor-β superfamily that is expressed in human granulosa cells and has important roles in regulating a variety of ovarian functions. GDF8 acts as a negative regulator of skeletal muscle growth and differentiation. In addition to the expression in the musculoskeletal system, GDF8 is also expressed in various tissues, including the reproductive system.

DETAILS

Tag: N-10×His
Host: HEK293
Size: 50ug
Buffer: PBS, pH7.4,0.2M Arg
Format: Powder
Purity: 90%
Source: Human latent GDF-8, His Tag (GD8-H5243) is expressed from human 293 cells (HEK293). It contains AA Asn 24 - Ser 375 (Accession # O14793-1).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: Latent GDF-8
Accession: NP_005250.1
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Asn 24 - Ser 375
Swiss-prot: O14793-1
Package Size: 50ug*1
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein migrates as 14kDa, 35 kDa and 45-50 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE), speculated as mature GDF-8, propeptide and latent GDF-8 respectively due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 42.0 kDa
Shipping Condition: RT
Species Reactivity: Human
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