DESCRIPTION

• Aa: 27-370
• Mw: 38.4 kDa
• Tags: C-terminal His-tag
• Notes: HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.
• Format: Aqueous buffer solution
• Genbank: NM_080792
• Species: Human
• Uniprot: P78324
• Shiptemp: -80°C (dry ice)
• Synonyms: CD172A, Tyrosine-protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1
• Warnings: Avoid freeze/thaw cycles. Protein may be diluted to _x0001_≥ 100 µg/ml in PBS + glycerol and stored at -80°C.
• Category: Cell Surface Receptor/Protein
• References: 1. Hatherley, D., et al., Mol. Cell, 2008, 31:266-772. Baba, N., et al., J. Exp. Med., 2013, 210(6):1251-63
• Description: Signal regulatory protein-alpha (SIRP-α), also known as Tyrosine-protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, GenBank Accession No. NM_080792, a.a. 27-370, with C-terminal His-tag, MW 38.4 kDa*, expressed in a HEK293 expression system. This protein acts as a receptor for CD47; a.a. 27-370 correspond to the extracellular portion of SIRP-α. *Note: SIRP-α is heavily glycosylated, resulting in apparent higher molecular weight.
• Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.4 mM KCl, and 20% glycerol
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Useful for studying protein binding and screening small molecules.
• Host Species: human
• Product Type: Protein
• Host Cell Line: HEK293
• Biosafety Level: Not applicable (BSL-1)
• Related Products: 71126
• Storage Stability: At least 6 months at -80°C.
• Scientific Category: Cell Surface Receptor
• Instructions for Use: Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening. Aliquot into small volumes and flash freeze for long term storage. Avoid multiple freeze/thaw cycles.