T62947
Lp-PLA2-IN-11
TargetMol
DETAILS
- Purity: 98%
- Smiles: O=C1N2C(=CC(OCC3=CC(F)=C(OC=4C=CC(C(F)(F)F)=NC4)C=C3)=N1)N(C)[C@H](C)CC2
- Category: Compounds
- Cas Number: 1620680-19-4
- Molecular Weight: 464.41
- Molecular Formula: C22H20F4N4O3
DESCRIPTION
Lp-PLA2-IN-11 is a potent inhibitor of lipoprotein-associated phospholipase A2 ( Lp-PLA2 ). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-11 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2014114249A1, compound E145) [1].
Lead Time: 4 - 5 weeks
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