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T62947

Lp-PLA2-IN-11

TargetMol

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DETAILS

  • Purity: 98%
  • Smiles: O=C1N2C(=CC(OCC3=CC(F)=C(OC=4C=CC(C(F)(F)F)=NC4)C=C3)=N1)N(C)[C@H](C)CC2
  • Category: Compounds
  • Cas Number: 1620680-19-4
  • Molecular Weight: 464.41
  • Molecular Formula: C22H20F4N4O3

DESCRIPTION

Lp-PLA2-IN-11 is a potent inhibitor of lipoprotein-associated phospholipase A2 ( Lp-PLA2 ). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-11 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2014114249A1, compound E145) [1].

Lead Time: 4 - 5 weeks

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