T83750
Melittin (C-Term Cysteine labeled) TFA
TargetMol
DESCRIPTION
Melittin (C-term cysteine labeled), a variant of the toxic bee venom peptide melittin featuring a cysteine residue at its C-terminus, effectively induces hemolysis in isolated human red blood cells at both endosomal and extracellular pH levels, with EC50 values of 5 µM at pH 5.5 and 6 µM at pH 7.4. This compound is utilized in creating membrane-lytic polymers for the synthesis of polyplexes, facilitating plasmid delivery both in vitro and in vivo.
DETAILS
- Purity: 98%
- Smiles: [H]NCC(N[C@]([C@H](CC)C)([H])C(NCC(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@]([C@@H](C)O)([H])C(N[C@]([C@@H](C)O)([H])C(NCC(N[C@@H](CC(C)C)C(N1CCC[C@H]1C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@]([C@H](CC)C)([H])C(N[C@@H](CO)C(N[C@H](C(N[C@]([C@H](CC)C)([H])C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N)=O)CS)=O)=O)=O)=O)=O)=O)=O)=O)CC2=CNC3=C2C=CC=C3)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C)=O)=O)=O.OC(C(F)(F)F)=O
- Category: Compound
- Molecular Weight: 2949.61
- Molecular Formula: C134H234N40O32S.XCF3COOH
Lead Time: 4 - 5 weeks
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