Cynomolgus IL-2 R beta / CD122 Protein, His Tag (MALS verified)

DESCRIPTION

Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2. The IL-2R is made up of 3 subunits - α (CD25), β (CD122) and γ (CD132) - non-covalently associating. The α and β chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ-chain, along with the β subunit. CD122 is also known as IL2R beta, is a member of the type I cytokine receptor family. CD122 is the receptor for interleukin-2 and is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

DETAILS

Tag: C-10×His
Host: HEK293
Size: 50ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Cynomolgus IL-2 R beta, His Tag (ILB-C52H9) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Thr 240 (Accession # Q38J85-1).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: IL-2 R beta
Accession: NP_001274237.1
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ala 27 - Thr 240
Swiss-prot: Q38J85-1
Package Size: 50ug*1
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.7 kDa. The protein migrates as 34-35 kDa and 36-38 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 26.7 kDa
Shipping Condition: RT
Species Reactivity: Cynomolgus
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