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5022822-10g 5022822-1g

Estradiol

Biogems

- Open Babel Depiction OH CH 3 HO

DESCRIPTION

Estradiol is the primary female sex hormone and cholesterol derivative. It acts as an agonist of the estrogen receptor (ER), activating both the ERalpha and ERbeta receptors.

DETAILS

  • Purity: ≥98%
  • Synonyms: 17β-estradiol, beta Estradiol, Aerodiol, Estrace, Estradiol 17beta, Oestradiol,
  • Cas Number: 50-28-2
  • References: Butcher, R. L., Collins, W. E., & Fugo, N. W. (1974). Plasma concentration of LH, FSH, prolactin, progesterone and estradiol-17β throughout the 4-day estrous cycle of the rat. Endocrinology, 94(6), 1704-1708. Pfaff, D., & Keiner, M. (1973). Atlas of estradiol‐concentrating cells in the central nervous system of the female rat. Journal of Comparative Neurology,151(2), 121-157. Hall, J. M., Couse, J. F., & Korach, K. S. (2001). The multifaceted mechanisms of estradiol and estrogen receptor signaling. Journal of Biological Chemistry, 276(40), 36869-36872.
  • Application: FA
  • Formulation: Crystalline solid
  • Chemical Name: (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
  • Molecular Weight: 272.4
  • Molecular Formula: C18H24O2
  • Storage Conditions: Product should be kept at -20°C.
  • Pubchem Openeye Can Smiles: CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O