Human BTK Protein, His Tag (active enzyme)

DESCRIPTION

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]

DETAILS

Tag: C-10×His
Host: InsectCells
Size: 50ug
Buffer: 50 mM Tris,150 mM NaCl, 1 mM DTT,PH7.5
Format: Liquid
Purity: 90%
Source: Human BTK Protein, His Tag (BTK-H55H3) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Ser 659 (Accession # Q06187-1).
Storage: -70℃
Category: Enzymes
Molecule: BTK
Conjugate: Unconjugated
Stability: ● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Exp Region: Met 1 - Ser 659
Swiss-prot: Q06187-1
Package Size: 50ug*1
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 78.2 kDa. The protein migrates as 55 kDa,65 kDa and 85-95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 78.2 kDa
Shipping Condition: Dry ice
Species Reactivity: Human
Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html