Keap1-Nrf2-IN-14

DESCRIPTION

Keap1-Nrf2-IN-14 is a KEAP1-NRF2 inhibitor that effectively disrupts the KEAP1-NRF2 interaction (IC50: 75 nM) with a Kd=24 nM for KEAP1. Keap1-Nrf2-IN-14 induces the expression of NRF2 target genes and is able to enhance downstream antioxidant and anti-inflammatory effects. -Nrf2-IN-14 can be used to study oxidative stress-related inflammation.

DETAILS

Cas: 1928782-31-3
Purity: 98%
Smiles: N(S(=O)(=O)C1=C(C)C=C(C)C=C1C)(CC(O)=O)C=2C3=C(C(OC(C(O)=O)C4=CC=C(OC)C=C4)=CC2)C=CC=C3
Category: Compound
Molecular Weight: 563.62
Molecular Formula: C30H29NO8S

Lead Time: Please Inquire