Human Cadherin-17 / CDH17 Protein, Fc Tag

DESCRIPTION

Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

DETAILS

Tag: C-Fc
Host: HEK293
Size: 1mg
Buffer: 20 mM Tris, 150 mM NaCl, pH8.0
Format: Powder
Purity: 90%
Source: Human Cadherin-17 Protein, Fc Tag (CA7-H5258) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Met 787 (Accession # Q12864-1).
Storage: -20℃
Category: Other Recombinant Proteins
Molecule: Cadherin-17
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Gln 23 - Met 787
Swiss-prot: Q12864-1
Package Size: 500ug*2
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 111.4 kDa. The protein migrates as 43-95 kDa and 130-150 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 111.4 kDa
Shipping Condition: RT
Species Reactivity: Human
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