Human B-cell Antigen Receptor Complex-associated Protein Alpha Chain, CD79A ELISA Kit

DESCRIPTION

Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.

DETAILS

GeneID: 973
Species: Human
Storage: 2-8ºC
MASS(Da): 25,038
Synonyms: B-cell antigen receptor complex-associated protein alpha chain;CD antigen CD79a;CD79A;IGA;Ig-alpha;MB-1;MB-1 membrane glycoprotein;Membrane-bound immunoglobulin-associated protein;Surface IgM-associated protein;
Assay Time: 1h 30m
Assay Type: Sandwich
Gene Names: CD79A
Reactivity: Human
Sample Type: Serum, plasma, cell culture supernates
Sensitivity: 9.99ng/L
Target Protein: CD79A
Detection Range: 20-3800ng/L
Full Product Name: B-cell antigen receptor complex-associated protein Alpha chain
Standard Solution: 4000ng/L
UniProt Accession: P11912