80070
DPP7, His-tag Recombinant
BPS Bioscience
DESCRIPTION
Human DPP7 (GenBank Accession No. NM_013379), a.a. 26-end with C-terminal His-tag, MW=52.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
DETAILS
- Aa: 26-end
- Mw: 52.5 kDa
- Tags: C-terminal His-tag
- Format: Aqueous buffer solution
- Genbank: NM_013379
- Species: Human
- Uniprot: Q9UHL4
- Shiptemp: -80°C (dry ice)
- Synonyms: Dipeptidylpeptidase 7, QPP, Carboxytripeptidase, DPP2
- Warnings: Avoid freeze/thaw cycles.
- Category: Protease/Protein
- Background: Dipeptidyl peptidase-7 (DPP7), also known as DPP2, is a serine aminopeptidase found in quiescent lymphocytes. Inhibition of this enzyme induces apoptosis, and levels of DPP7 are elevated in many tumors, suggesting that DPP7 may be involved in a novel pathway for tumor suppression.
- References: 1. Shreder K.R. et al., Bioorg Med Chem Lett. 2005 Oct 1;15(19):4256-60.2. Maes M.B. et al., Biochem J. 2005 Mar 1;386(Pt 2):315-24.
- Description: Human DPP7 (GenBank Accession No. NM_013379), a.a. 26-end with C-terminal His-tag, MW=52.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
- Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 220 mM imidazole, and 20% glycerol
- Unspsc Code: 12352202
- Unspsc Name: Proteins
- Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
- Product Type: Protein
- Biosafety Level: Not applicable (BSL-1)
- Assay Conditions: 10 mM Tris-HCl, pH 7.4,_x000D_ 10 mM MgCl2, 1 mM MnCl2, 20 µM Ala-Pro-AMC,_x000D_ 10 min, room temperature.
- Specific Activity: ≥ 1880 pmol/min/µg.
- Storage Stability: At least 6 months at -80°C.
- Scientific Category: Protease