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80070

DPP7, His-tag Recombinant

BPS Bioscience

DESCRIPTION

Human DPP7 (GenBank Accession No. NM_013379), a.a. 26-end with C-terminal His-tag, MW=52.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

DETAILS

  • Aa: 26-end
  • Mw: 52.5 kDa
  • Tags: C-terminal His-tag
  • Format: Aqueous buffer solution
  • Genbank: NM_013379
  • Species: Human
  • Uniprot: Q9UHL4
  • Shiptemp: -80°C (dry ice)
  • Synonyms: Dipeptidylpeptidase 7, QPP, Carboxytripeptidase, DPP2
  • Warnings: Avoid freeze/thaw cycles.
  • Category: Protease/Protein
  • Background: Dipeptidyl peptidase-7 (DPP7), also known as DPP2, is a serine aminopeptidase found in quiescent lymphocytes. Inhibition of this enzyme induces apoptosis, and levels of DPP7 are elevated in many tumors, suggesting that DPP7 may be involved in a novel pathway for tumor suppression.
  • References: 1. Shreder K.R. et al., Bioorg Med Chem Lett. 2005 Oct 1;15(19):4256-60.2. Maes M.B. et al., Biochem J. 2005 Mar 1;386(Pt 2):315-24.
  • Description: Human DPP7 (GenBank Accession No. NM_013379), a.a. 26-end with C-terminal His-tag, MW=52.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
  • Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 220 mM imidazole, and 20% glycerol
  • Unspsc Code: 12352202
  • Unspsc Name: Proteins
  • Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. 
  • Product Type: Protein
  • Biosafety Level: Not applicable (BSL-1)
  • Assay Conditions: 10 mM Tris-HCl, pH 7.4,_x000D_ 10 mM MgCl2, 1 mM MnCl2, 20 µM Ala-Pro-AMC,_x000D_ 10 min, room temperature.
  • Specific Activity: ≥ 1880 pmol/min/µg.
  • Storage Stability: At least 6 months at -80°C.
  • Scientific Category: Protease