T79689
SIRT6-IN-3
TargetMol
DESCRIPTION
SIRT6-IN-3 (compound 8a), a selective SIRT6 inhibitor (IC50 = 7.49 μM), impedes the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and prompts apoptosis. It enhances the responsiveness of cancer cells to gemcitabine by obstructing the DNA damage repair pathway, thus serving as a valuable tool in pancreatic cancer research [1].
DETAILS
- Cas: 3023471-40-8
- Purity: 98%
- Smiles: [Br-].Cl.BrC=1C=C(NC1Br)C2=NC=CC3=C2N=CN3CCCCCCSC(N(C)C)=[N+](C)C
- Category: Compound
- Molecular Weight: 673.73
- Molecular Formula: C21H30Br3ClN6S
Lead Time: 4 - 5 weeks
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