6083373-500mg 6083373-50mg
Sinomenine hydrochloride
Biogems
DETAILS
- Purity: ≥98%
- Synonyms: cocculine hydrochloride, NSC 76021, NSC76021
- Cas Number: 6080-33-7
- References: Liu, L., Resch, K., & Kaever, V. (1994). Inhibition of lymphocyte proliferation by the anti-arthritic drug sinomenine. International journal of immunopharmacology,16(8), 685-691. Vieregge, B., Resch, K., & Kaever, V. (1999). Synergistic effects of the alkaloid sinomenine in combination with the immunosuppressive drugs tacrolimus and mycophenolic acid. Planta medica, 65(1), 80-82. Wang, Y., Fang, Y., Huang, W., Zhou, X., Wang, M., Zhong, B., & Peng, D. (2005). Effect of sinomenine on cytokine expression of macrophages and synoviocytes in adjuvant arthritis rats. Journal of ethnopharmacology, 98(1), 37-43. Desbordes, S. C., Placantonakis, D. G., Ciro, A., Socci, N. D., Lee, G., Djaballah, H., & Studer, L. (2008). High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell stem cell, 2(6), 602-612.
- Application: FA
- Formulation: Crystalline solid
- Chemical Name: 9-alpha,13-alpha,14-alpha-Morphinan-6-one,7,8-didehydro-3,7-dimethoxy-4-hydroxy-17-methyl-,hydrochloride
- Molecular Weight: 365.9
- Molecular Formula: C19H23NO4HCl
- Storage Conditions: Product should be kept at -20°C.
- Pubchem Openeye Can Smiles: CN1CCC23CC(=O)C(=CC2C1CC4=C3C(=C(C=C4)OC)O)OC.Cl
DESCRIPTION
Sinomenine is an anti-inflammatory plant alkaloid that suppresses the production of proinflammatory cytokines and ease arthritis inflammation. It is reported to also be used to promote the self-renewal of embryonic stem cells