DESCRIPTION

• Shiptemp: -80°C (dry ice)
• Synonyms: matrix metalloproteinase 10 kit, MMP-10 assay kit, Stromelysin-2 kit
• Warnings: Avoid freeze/thaw cycles.
• Category: Proteases/Assay Kit
• Background: MMP10 (matrix metalloproteinase 10), also known as Stromelysin-2, is a member of the matrix metalloproteinase (MMP) family involved in the degradation of the extracellular matrix. MMP10 moderates inflammation by controlling macrophage activation and is linked to several lung disorders, including pulmonary fibrosis and cystic fibrosis. MMP10 has also been shown to cleave the mutant huntingtin protein associated with Huntington's disease.
• References: 1. Batra, J. et al. Matrix Metalloproteinase-10/TIMP-2 Structure and Analyses Define Conserved Core Interactions and Diverse Exosite Interactions in MMP/TIMP Complexes. PLoS One. 2013 Sep 20; 8(9):e75836.2. McMahan, R.S., et al. Stromelysin-2 (MMP10) Moderates Inflammation by Controlling Macrophage Activation. J. Immunol. August 1, 2016, 197(3): 899-909.
• Description: The Fluorogenic MMP10 Assay Kit is designed to measure MMP10 activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps. 
• Methodology: Fluorogenic
• Supplied As: The kit comes in a convenient 96-well format, with purified MMP10 enzyme, fluorogenic substrate, and MMP assay buffer for 100 enzyme reactions.
• Unspsc Code: 41105331
• Unspsc Name: Protein chemifluorescent detection reagents or kits or substrates
• Applications: Great for studying enzyme kinetics and HTS applications.
• Product Type: Assay Kit
• Biosafety Level: Not applicable (BSL-1)
• Related Products: 80213, 80214, 79929, 79983
• Storage Stability: At least one year from date of receipt when stored as directed.
• Scientific Category: Protease
• Instructions for Use: See assay protocol for detailed instructions.